Regulatory tracker

FDA kratom timeline.

The FDA has taken escalating regulatory action against kratom and its alkaloids since 2012. The July 29, 2025 announcement that FDA plans to restrict 7-hydroxymitragynine (7-OH) is the most significant enforcement action to date. Leaf kratom remains federally legal. This page tracks warning letters, import alerts, recalls, and scheduling announcements in reverse-chronological order. Sources: FDA.gov, Pharmacy Times, Venable Law analysis.

State bans: 6
12+ Warning letters issued
2025 7-OH restriction announced
Leaf still federally legal
  1. 2025-07-29

    scheduling

    FDA announces plan to restrict 7-OH

    FDA announced regulatory action to restrict 7-hydroxymitragynine (7-OH) products, including warning letters to multiple firms and preparation for scheduling action. Leaf kratom not affected by this announcement.

    View source: FDA press announcement
  2. 2025-07-15

    warning

    FDA issues warning letters to 7-OH manufacturers

    FDA sent warning letters to firms marketing 7-hydroxymitragynine-containing products as unapproved new drugs. Products flagged included tablets, gummies, and concentrated extracts.

    View source: FDA press release
  3. 2024-08-01

    advisory

    FDA renewed public health advisory

    FDA reiterated its position that kratom should not be used to treat medical conditions and warned of adverse events associated with kratom use, including seizures and liver toxicity.

    View source: FDA.gov kratom hub
  4. 2022-03-28

    recall

    Multiple kratom recalls for salmonella

    Recalls initiated across multiple kratom brands after positive salmonella test results in imported leaf material.

    View source: FDA
  5. 2018-04-03

    recall

    Salmonella outbreak linked to kratom

    FDA investigated a multistate salmonella outbreak linked to kratom products. 28 states affected, 199 people sickened.

    View source: FDA
  6. 2018-02-06

    advisory

    FDA Commissioner Scott Gottlieb statement on kratom

    Then-FDA Commissioner Gottlieb issued a strong statement warning about kratom's opioid-like properties, citing 44 reported deaths associated with kratom use.

    View source: FDA
  7. 2016-10-12

    scheduling

    DEA withdraws Schedule I proposal

    Following public outcry and pushback from scientists, advocates, and members of Congress, the DEA withdrew its intent-to-schedule notice for kratom alkaloids.

    View source: DEA
  8. 2016-08-26

    scheduling

    DEA announces intent to schedule kratom as Schedule I

    DEA issued notice of intent to temporarily place mitragynine and 7-hydroxymitragynine in Schedule I of the Controlled Substances Act.

    View source: Federal Register
  9. 2014-02-11

    advisory

    FDA import alert — kratom

    FDA issued import alert 54-15 authorizing detention without physical examination of shipments of kratom and kratom products.

    View source: FDA import alerts